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A Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Switching From Tenofovir Disoproxil Fumarate (TDF) 300 mg QD to Tenofovir Alafenamide (TAF) 25 mg QD in Subjects With Chronic Hepatitis B Who Are Virologically Suppressed

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Trial Profile

A Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Switching From Tenofovir Disoproxil Fumarate (TDF) 300 mg QD to Tenofovir Alafenamide (TAF) 25 mg QD in Subjects With Chronic Hepatitis B Who Are Virologically Suppressed

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 08 Aug 2023

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At a glance

  • Drugs Tenofovir alafenamide (Primary) ; Tenofovir disoproxil fumarate
  • Indications Hepatitis B
  • Focus Registrational; Therapeutic Use
  • Sponsors Gilead Sciences

    • Most Recent Events

    • 24 Jun 2023 Results of pooled analysis of 3 studies assessing 8-year results of long-term safety profile of tenofovir alafenamide in chronic hepatitis B patients, presented at the European Association for the Study of the Liver Congress 2023.
    • 28 Oct 2020 Results reporting final efficacy and safety from this study at Week 96 presented at the American College of Gastroenterology Annual Scientific Meeting and Postgraduate Course 2020
    • 29 Aug 2020 Results of safety and efficacy at 96 weeks presented at The International Liver Congress 2020

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