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A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Progressive Supranuclear Palsy

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Progressive Supranuclear Palsy

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 15 Mar 2021

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At a glance

  • Drugs Tilavonemab (Primary)
  • Indications Progressive supranuclear palsy
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors AbbVie

    • Most Recent Events

    • 01 Mar 2021 Primary endpoint has not been met. (Change From Baseline to Week 52 in Progressive Supranuclear Palsy Rating Scale (PSPRS) Total Score), as per Results published in the Lancet Neurology
    • 01 Mar 2021 Results published in the Lancet Neurology
    • 01 Feb 2021 Status changed from completed to discontinued.

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