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A Phase 3, Randomized, Rater-Blinded, Multi-Center Study to Evaluate the Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Patients With Wilson Disease Aged 12 Years and Older, With an Extension Period of up to 60 Months

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Trial Profile

A Phase 3, Randomized, Rater-Blinded, Multi-Center Study to Evaluate the Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Patients With Wilson Disease Aged 12 Years and Older, With an Extension Period of up to 60 Months

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 19 Jun 2024

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At a glance

  • Drugs Tiomolibdate choline (Primary) ; Penicillamine; Trientine; Zinc acetate
  • Indications Hepatolenticular degeneration
  • Focus Registrational; Therapeutic Use
  • Acronyms FOCUS
  • Sponsors Alexion AstraZeneca Rare Disease; Wilson Therapeutics
  • Most Recent Events

    • 30 Dec 2023 This trial has been completed in France (Global end date: 30 June 2023).
    • 01 Aug 2023 Status changed from active, no longer recruiting to discontinued as per sponsor decision to terminate the program.
    • 23 May 2023 This trial has been discontinued in Austria and Spain, according to European Clinical Trials Database record.

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