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Open Label, Phase II Trial of Neoadjuvant TAK-228 Plus Tamoxifen in Patients With Estrogen Receptor (ER)-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer

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Trial Profile

Open Label, Phase II Trial of Neoadjuvant TAK-228 Plus Tamoxifen in Patients With Estrogen Receptor (ER)-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 Sep 2021

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At a glance

  • Drugs Sapanisertib (Primary) ; Tamoxifen (Primary)
  • Indications Advanced breast cancer; Early breast cancer; HER2 negative breast cancer
  • Focus Pharmacodynamics
  • Acronyms ANETT
  • Most Recent Events

    • 01 Jul 2021 Results published in the Breast Cancer Research and Treatment
    • 04 Jun 2019 Primary endpoint has been met. (Change in Ki67 after 6 weeks), as reported in an abstract presented at the 55th Annual Meeting of the American Society of Clinical Oncology
    • 04 Jun 2019 Results presented at the 55th Annual Meeting of the American Society of Clinical Oncology

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