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A Pilot Safety Study and Single Arm Phase II Study of Gemcitabine and Cisplatin with Atezolizumab (MPDL3280A) in Patients with Metastatic and Muscle Invasive Bladder Cancer, Respectively

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Trial Profile

A Pilot Safety Study and Single Arm Phase II Study of Gemcitabine and Cisplatin with Atezolizumab (MPDL3280A) in Patients with Metastatic and Muscle Invasive Bladder Cancer, Respectively

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 30 Oct 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; Cisplatin (Primary) ; Gemcitabine (Primary)
  • Indications Bladder cancer; Carcinoma; Pelvic cancer; Ureteral neoplasms; Urethral cancer; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 28 Feb 2024 Planned End Date changed from 1 Dec 2023 to 1 Dec 2024.
    • 28 Feb 2024 Planned primary completion date changed from 1 Dec 2023 to 1 Dec 2024.
    • 01 May 2023 Results of the perioperative outcomes of the GC+A cohort compared to a matched cohortof patients with MIBC who received GC, presented at the 118th Annual Meeting of the American Urological Association

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