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Impact of concomitant Methotrexate on efficacy, safety and adherence of Ustekinumab-treatment in patients with active Psoriatic Arthritis (MUST-Study)

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Trial Profile

Impact of concomitant Methotrexate on efficacy, safety and adherence of Ustekinumab-treatment in patients with active Psoriatic Arthritis (MUST-Study)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 Apr 2023

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At a glance

  • Drugs Ustekinumab (Primary) ; Methotrexate
  • Indications Psoriatic arthritis
  • Focus Therapeutic Use
  • Acronyms MUST-Study
  • Most Recent Events

    • 20 Apr 2023 Results of post-hoc analysis on 112 psoriatic arthritis serum samples of subjects treated with open-label Ustekinumab and either concomitant Methotrexate published in the Rheumatology
    • 14 Nov 2022 Results of a sub-group analysis assessing differences in response rates to pain and ACR response between male and female and treatment groups (UST+MTX or UST only) using data from this trial presented at the ACR Convergence 2022
    • 04 Jun 2022 Results of post-hoc analysis assessing the impact of concomitant methotrexate on ustekinumab-immunogenicity in patients with active psoriatic arthritis, presented at the 23rd Annual Congress of the European League Against Rheumatism.

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