A Multicenter, Randomized, Placebo-controlled, Parallel Group, Double Blind, Dose-finding Phase II Trial to Study the Efficacy, Safety, Pharmacokinetic and Pharmacodynamic Effects of the Oral Partial Adenosine A1 Receptor Agonist Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Reduced Ejection Fraction

Trial Profile

A Multicenter, Randomized, Placebo-controlled, Parallel Group, Double Blind, Dose-finding Phase II Trial to Study the Efficacy, Safety, Pharmacokinetic and Pharmacodynamic Effects of the Oral Partial Adenosine A1 Receptor Agonist Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Reduced Ejection Fraction

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Apr 2018

At a glance

  • Drugs BAY 1067197 (Primary)
  • Indications Chronic heart failure
  • Focus Therapeutic Use
  • Acronyms PANTHEON
  • Sponsors Bayer
  • Most Recent Events

    • 04 Apr 2018 Planned End Date changed from 8 May 2018 to 17 May 2018.
    • 30 Nov 2017 Status changed from recruiting to active, no longer recruiting.
    • 26 Oct 2017 Planned End Date changed from 7 Jun 2018 to 8 May 2018.
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