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A Phase Ib Open-Label, Dose-Finding Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Avelumab in Combination With M9241(NHS-IL12) in Subjects With Locally Advanced, Unresectable, or Metastatic Solid Tumors

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Trial Profile

A Phase Ib Open-Label, Dose-Finding Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Avelumab in Combination With M9241(NHS-IL12) in Subjects With Locally Advanced, Unresectable, or Metastatic Solid Tumors

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Avelumab (Primary) ; PDS 0301 (Primary)
  • Indications Colorectal cancer; Non-small cell lung cancer; Renal cell carcinoma; Solid tumours; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms COMBO
  • Sponsors EMD Serono
  • Most Recent Events

    • 15 Dec 2020 Status changed from active, no longer recruiting to discontinued.
    • 20 May 2020 Status changed from recruiting to active, no longer recruiting.
    • 25 Nov 2019 Planned number of patients changed from 185 to 106.
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