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A Phase 1, Open-Label, Dose-Escalation Clinical Trial of Tumor Necrosis Factor Alpha and Interleukin 2 Coding Oncolytic Adenovirus TILT-123 in Melanoma Patients Receiving Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes

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A Phase 1, Open-Label, Dose-Escalation Clinical Trial of Tumor Necrosis Factor Alpha and Interleukin 2 Coding Oncolytic Adenovirus TILT-123 in Melanoma Patients Receiving Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Mar 2024

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At a glance

  • Drugs Igrelimogene litadenorepvec (Primary) ; Igrelimogene litadenorepvec (Primary)
  • Indications Malignant melanoma
  • Focus Adverse reactions; First in man
  • Acronyms TUNINTIL
  • Sponsors TILT Biotherapeutics

    • Most Recent Events

    • 08 Mar 2024 Planned End Date changed from 1 Feb 2025 to 1 Dec 2024.
    • 08 Mar 2024 Status changed from recruiting to active, no longer recruiting.
    • 08 Dec 2023 According to a TILT Biotherapeutics media release, company presented safety and efficacy data from this trail in an oral presentation at the ESMO Immuno-Oncology Congress (ESMO-IO) in Geneva, Switzerland (6-8 December).

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