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Trial Profile

HyPeR: A Phase 1, Dose Escalation Study of Guadecitabine /ASTX727 in Combination With Pembrolizumab (MK3475) in Patients With Refractory Solid Tumours

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 22 Mar 2024

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At a glance

Drugs Guadecitabine (Primary) ; Pembrolizumab (Primary)
Indications Non-small cell lung cancer; Prostate cancer; Solid tumours
Focus Adverse reactions
Acronyms HyPeR

Most Recent Events

19 Mar 2024 Status has been to recruiting.
17 Oct 2023 Number of treatment arms have been increased from 2 to 3 by the addition of Experimental: B2: Lung Expansion arm.
17 Oct 2023 Planned End Date changed from 1 Sep 2024 to 1 Sep 2026.

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