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A Phase II Trial Testing Durvalumab Combined With Endocrine Therapy in Patients With ER+/Her2- Breast Cancer Eligible for Neoadjuvant Endocrine Therapy And Who Present CD8+ T Cell Infiltration After 4-6 Weeks Exposure to Immune-Attractant

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A Phase II Trial Testing Durvalumab Combined With Endocrine Therapy in Patients With ER+/Her2- Breast Cancer Eligible for Neoadjuvant Endocrine Therapy And Who Present CD8+ T Cell Infiltration After 4-6 Weeks Exposure to Immune-Attractant

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 13 Apr 2022

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At a glance

  • Drugs Durvalumab (Primary) ; Exemestane (Primary) ; Tremelimumab (Primary)
  • Indications Early breast cancer
  • Focus Therapeutic Use
  • Acronyms ULTIMATE

    • Most Recent Events

    • 29 Sep 2020 Status changed from active, no longer recruiting to completed.
    • 05 Sep 2020 This trial has been completed in France, according to European Clinical Trials Database record.
    • 02 Oct 2019 Planned primary completion date changed from 1 Sep 2019 to 1 Jan 2020.

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