Colorectal Cancer Metastatic dMMR/MSI-H Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab/Atezolizumab Combination Versus Single Agent Atezolizumab in the First-Line Treatment of Patients With Deficient DNA Mismatch Repair (dMMR)/Microsatellite Instability-High (MSI-H) Metastatic Colorectal Cancer
Latest Information Update: 30 Oct 2024
At a glance
- Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
- Indications Adenocarcinoma; Colon cancer; Colorectal cancer; Rectal cancer
- Focus Therapeutic Use
- Acronyms COMMIT
- 04 Jun 2024 Study design presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
- 20 Jan 2024 Trial design, presented at the 2024 Gastrointestinal Cancers Symposium
- 30 Mar 2023 Planned number of patients changed from 231 to 120.