Trial Profile

Colorectal Cancer Metastatic dMMR/MSI-H Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab/Atezolizumab Combination Versus Single Agent Atezolizumab in the First-Line Treatment of Patients With Deficient DNA Mismatch Repair (dMMR)/Microsatellite Instability-High (MSI-H) Metastatic Colorectal Cancer

Status: Suspended

Phase of Trial: Phase III

Latest Information Update: 07 Apr 2025

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At a glance

Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
Indications Adenocarcinoma; Colon cancer; Colorectal cancer; Rectal cancer
Focus Therapeutic Use
Acronyms COMMIT

02 Apr 2025 Status changed from recruiting to suspended.
27 Jan 2025 Planned End Date changed from 30 Nov 2024 to 1 Jun 2027.
27 Jan 2025 Planned primary completion date changed from 30 Nov 2024 to 1 Jun 2027.

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