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A Phase III Randomized, Open-Label, Multi-Center Study of Durvalumab (MEDI4736) Versus Standard of Care (SoC) Platinum-Based Chemotherapy as First Line Treatment in Patients With PD-L1-High Expression Advanced Non Small-Cell Lung Cancer

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A Phase III Randomized, Open-Label, Multi-Center Study of Durvalumab (MEDI4736) Versus Standard of Care (SoC) Platinum-Based Chemotherapy as First Line Treatment in Patients With PD-L1-High Expression Advanced Non Small-Cell Lung Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Sep 2024

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At a glance

  • Drugs Durvalumab (Primary) ; Carboplatin; Cisplatin; Gemcitabine; Paclitaxel; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms PEARL
  • Sponsors AstraZeneca; AstraZeneca AB

    • Most Recent Events

    • 19 Aug 2024 Planned End Date changed from 3 Jun 2026 to 30 Jun 2026.
    • 19 Apr 2024 Planned End Date changed from 4 Jun 2026 to 3 Jun 2026.
    • 28 Dec 2023 Planned End Date changed from 20 Aug 2026 to 4 Jun 2026.

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