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Phase 2 Study of Epacadostat, Pembrolizumab, and CRS-207, With or Without Cyclophosphamide and GVAX Pancreas Vaccine in Patients With Metastatic Pancreas Cancer

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Trial Profile

Phase 2 Study of Epacadostat, Pembrolizumab, and CRS-207, With or Without Cyclophosphamide and GVAX Pancreas Vaccine in Patients With Metastatic Pancreas Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 24 Jun 2024

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At a glance

  • Drugs CRS 207 (Primary) ; Cyclophosphamide (Primary) ; Epacadostat (Primary) ; Pembrolizumab (Primary) ; Tumour cell vaccine-GVAX (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 28 May 2024 Given protocol has been amended as above-1) Parallel Assignment has been amended in study design. 2) primary endpoints has been amended.
    • 28 May 2024 Planned End Date changed from 1 Dec 2024 to 22 Aug 2024.
    • 02 Jan 2024 Planned End Date changed from 1 Dec 2023 to 1 Dec 2024.

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