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A Phase 2, Randomized, Dose-Ranging, Vehicle-Controlled and Triamcinolone 0.1% Cream-Controlled Study to Evaluate the Safety and Efficacy of INCB018424 Phosphate Cream Applied Topically to Adults With Atopic Dermatitis

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Trial Profile

A Phase 2, Randomized, Dose-Ranging, Vehicle-Controlled and Triamcinolone 0.1% Cream-Controlled Study to Evaluate the Safety and Efficacy of INCB018424 Phosphate Cream Applied Topically to Adults With Atopic Dermatitis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 24 Jun 2021

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At a glance

  • Drugs Ruxolitinib (Primary) ; Triamcinolone
  • Indications Atopic dermatitis
  • Focus Therapeutic Use
  • Sponsors Incyte Corporation

    • Most Recent Events

    • 12 May 2021 Results of a pooled analysis ( of data from a phase II NCT03011892 and two (NCT03745638 & NCT03745651) phase III studies) assessing the pharmacokinetics of Ruxolitinib published in the American Journal of Clinical Dermatology
    • 11 Feb 2020 Results assessing Effects of Ruxolitinib Cream on Pruritus and Quality of Life in Atopic Dermatitis, published in the Journal of the American Academy of Dermatology
    • 17 Oct 2019 Primary endpoint (mean percentage change from baseline in EASI score versus vehicle at Week 4) has been met as per results published at Journal of Allergy and Clinical Immunology.

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