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Pharmacokinetics of Tenofovir in Blood, Plasma and Urine of Healthy Adults With Perfect, Median and Low Drug Adherence

Trial Profile

Pharmacokinetics of Tenofovir in Blood, Plasma and Urine of Healthy Adults With Perfect, Median and Low Drug Adherence

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Emtricitabine/tenofovir disoproxil fumarate (Primary)
  • Indications HIV infections
  • Focus Pharmacokinetics
  • Acronyms TARGET
  • Most Recent Events

    • 21 Apr 2021 Results (n=36) assessing urine tenofovir levels among individuals taking tenofovir alafenamide at variable dosing intervals, and compare them to a prior study of directly observed therapy tenofovir disoproxil fumarate, presented at the 28th Conference on Retroviruses and Opportunistic Infections.
    • 17 Jul 2019 Results to estimate the correlation between urine and plasma TFV concentrations in a randomized directly-observed pharmacokinetic study published in the Clinical Infectious Diseases
    • 21 Mar 2018 Status changed from recruiting to completed.
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