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Pharmacokinetics of Tenofovir in Blood, Plasma and Urine of Healthy Adults With Perfect, Median and Low Drug Adherence

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Trial Profile

Pharmacokinetics of Tenofovir in Blood, Plasma and Urine of Healthy Adults With Perfect, Median and Low Drug Adherence

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Emtricitabine/tenofovir disoproxil fumarate (Primary)
  • Indications HIV infections
  • Focus Pharmacokinetics
  • Acronyms TARGET
  • Most Recent Events

    • 21 Apr 2021 Results (n=36) assessing urine tenofovir levels among individuals taking tenofovir alafenamide at variable dosing intervals, and compare them to a prior study of directly observed therapy tenofovir disoproxil fumarate, presented at the 28th Conference on Retroviruses and Opportunistic Infections.
    • 17 Jul 2019 Results to estimate the correlation between urine and plasma TFV concentrations in a randomized directly-observed pharmacokinetic study published in the Clinical Infectious Diseases
    • 21 Mar 2018 Status changed from recruiting to completed.
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