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A Phase II Study of Cisplatin + AZD1775 in Metastatic Triple-negative Breast Cancer and Evaluation of pCDC2 as a Biomarker of Target Response

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Trial Profile

A Phase II Study of Cisplatin + AZD1775 in Metastatic Triple-negative Breast Cancer and Evaluation of pCDC2 as a Biomarker of Target Response

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Nov 2021

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At a glance

  • Drugs Adavosertib (Primary) ; Cisplatin (Primary)
  • Indications Advanced breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 25 Jun 2021 Status changed from active, no longer recruiting to completed.
    • 27 May 2021 Planned End Date changed from 1 Dec 2024 to 1 Sep 2021.
    • 30 Nov 2020 Results assessing efficacy and molecular response of adavosertib with cisplatin in metastatic triple-negative breast cancer patients from this trial published in the Clinical Cancer Research

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