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A Randomized, Open-Label, Phase 3 Study to Evaluate Efficacy and Safety of Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care (Sunitinib or Pazopanib) as First-Line Treatment for Locally Advanced or Metastatic Renal Cell Carcinoma (mRCC) (KEYNOTE-679/ECHO-302)

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A Randomized, Open-Label, Phase 3 Study to Evaluate Efficacy and Safety of Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care (Sunitinib or Pazopanib) as First-Line Treatment for Locally Advanced or Metastatic Renal Cell Carcinoma (mRCC) (KEYNOTE-679/ECHO-302)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 08 Aug 2024

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At a glance

  • Drugs Epacadostat (Primary) ; Pembrolizumab (Primary) ; Pazopanib; Sunitinib
  • Indications Renal cell carcinoma
  • Focus Registrational; Therapeutic Use
  • Acronyms KEYNOTE-679/ECHO-302
  • Sponsors Incyte Corporation

    • Most Recent Events

    • 25 Jul 2024 Results assessing comparison of pembrolizumab plus epacadostat with sunitinib or pazopanib as first-line treatment for mRCC presented in the BMC Cancer
    • 15 May 2023 Planned End Date changed from 4 Feb 2023 to 31 Dec 2024.
    • 01 Jul 2022 This trial has been completed in Hungary, according to European Clinical Trials Database record

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