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A Phase III, Randomized, Open-label Clinical Trial of Pembrolizumab (MK-3475) Versus Paclitaxel in Asian Subjects With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Who Progressed After First-Line Therapy With Platinum and Fluoropyrimidine

Trial Profile

A Phase III, Randomized, Open-label Clinical Trial of Pembrolizumab (MK-3475) Versus Paclitaxel in Asian Subjects With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Who Progressed After First-Line Therapy With Platinum and Fluoropyrimidine

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 03 Apr 2023

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At a glance

  • Drugs Pembrolizumab (Primary) ; Paclitaxel
  • Indications Adenocarcinoma; Carcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use
  • Acronyms KEYNOTE-063
  • Sponsors Merck Sharp & Dohme Corp.
  • Most Recent Events

    • 08 Dec 2021 Results assessing the efficacy of second-line pembrolizumab in Asian patients with advanced PD L1 positive gastric/GEJ cancer, published in the Cancer.
    • 31 May 2020 Status changed from active, no longer recruiting to discontinued, according to the results presented at the 56th Annual Meeting of the American Society of Clinical Oncology.
    • 31 May 2020 Results presented at the 56th Annual Meeting of the American Society of Clinical Oncology
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