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BLAM- A phase IIb study of Blinatumomab + Cytarabine (AraC) and Methotrexate in adult B-precursor Acute Lymphoblastic Leukaemia

Trial Profile

BLAM- A phase IIb study of Blinatumomab + Cytarabine (AraC) and Methotrexate in adult B-precursor Acute Lymphoblastic Leukaemia

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Jul 2023

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At a glance

  • Drugs Blinatumomab (Primary) ; Cyclophosphamide; Cytarabine; Cytarabine; Dexamethasone; Hydrocortisone; Mercaptopurine; Methotrexate; Methotrexate; Methotrexate; Methylprednisolone; Prednisolone; Vincristine; Vincristine
  • Indications Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Proof of concept; Therapeutic Use
  • Acronyms BLAM
  • Most Recent Events

    • 15 Jun 2023 Results of an analysis of the final endpoint at 14 Feb 2023; n=30 presented at the 28th Congress of the European Haematology Association
    • 14 Dec 2021 Interim results (n=30 ) presented at the 63rd American Society of Hematology Annual Meeting and Exposition
    • 06 Nov 2019 Results assessing response to therapy of the first 10 patients enrolled on this study, released in 61st Annual Meeting and Exposition of the American Society of Hematology
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