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A Clinical Trial to Investigate Biomarker Effects of Pre-Surgical Treatment With DDR Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC) Who Are Planned to Undergo Surgery That is Likely to be Followed by Radiotherapy and/or Chemotherapy

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A Clinical Trial to Investigate Biomarker Effects of Pre-Surgical Treatment With DDR Agents in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC) Who Are Planned to Undergo Surgery That is Likely to be Followed by Radiotherapy and/or Chemotherapy

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 May 2023

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At a glance

  • Drugs Ceralasertib (Primary) ; Olaparib (Primary)
  • Indications Carcinoma; Head and neck cancer; Squamous cell cancer
  • Focus Biomarker; Pharmacodynamics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 19 Apr 2023 Results presented at the 114th Annual Meeting of the American Association for Cancer Research
    • 01 Mar 2021 Status changed to completed.
    • 09 Oct 2020 Planned number of patients increased from 40 to 50.

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