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A Single-center, Randomized, Open-label, Two-arm Study to Evaluate the Ovarian Function Inhibition of a Monophasic Combined Oral Contraceptive (COC) Containing 15 mg Estetrol (E4) and 3 mg Drospirenone (DRSP) and a Monophasic COC Containing 20mcg Ethinylestradiol (EE)/3 mg DRSP (YAZ), Administered Orally Once Daily in a 24/4 Day Regimen for Three Consecutive Cycles

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A Single-center, Randomized, Open-label, Two-arm Study to Evaluate the Ovarian Function Inhibition of a Monophasic Combined Oral Contraceptive (COC) Containing 15 mg Estetrol (E4) and 3 mg Drospirenone (DRSP) and a Monophasic COC Containing 20mcg Ethinylestradiol (EE)/3 mg DRSP (YAZ), Administered Orally Once Daily in a 24/4 Day Regimen for Three Consecutive Cycles

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 May 2023

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At a glance

  • Drugs Drospirenone/estetrol (Primary) ; Drospirenone/ethinylestradiol
  • Indications Pregnancy
  • Focus Therapeutic Use
  • Sponsors Estetra SPRL

    • Most Recent Events

    • 23 Mar 2021 Results presented at the 103rd Annual Meeting of the Endocrine Society
    • 06 Mar 2021 Results published in the Contraception
    • 22 Jun 2018 Status changed from active, no longer recruiting to completed.

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