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A PHASE III, MULTICENTER, RANDOMIZED STUDY OF ATEZOLIZUMAB VERSUS PLACEBO ADMINISTERED IN COMBINATION WITH PACLITAXEL, CARBOPLATIN, AND BEVACIZUMAB FOR PATIENTS WITH NEWLY-DIAGNOSED STAGE III OR STAGE IV OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER

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Trial Profile

A PHASE III, MULTICENTER, RANDOMIZED STUDY OF ATEZOLIZUMAB VERSUS PLACEBO ADMINISTERED IN COMBINATION WITH PACLITAXEL, CARBOPLATIN, AND BEVACIZUMAB FOR PATIENTS WITH NEWLY-DIAGNOSED STAGE III OR STAGE IV OVARIAN, FALLOPIAN TUBE, OR PRIMARY PERITONEAL CANCER

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 03 Oct 2023

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At a glance

  • Drugs Atezolizumab (Primary) ; Bevacizumab; Carboplatin; Paclitaxel
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms IMagyn050
  • Sponsors Chugai Pharmaceutical; Genentech; Roche
  • Most Recent Events

    • 23 Aug 2023 Primary endpoint (Overall Survival - PD-L1Positive Subpopulation) has not been met according to published in the Gynecologic Oncology.
    • 23 Aug 2023 Results assessing impact on overall survival (OS) and patient-reported outcomes (PROs) of combining atezolizumab with standard therapy for newly diagnosed stage III/IV ovarian cancer published in the Gynecologic Oncology.
    • 19 Apr 2023 Results presented at the 114th Annual Meeting of the American Association for Cancer Research

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