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A Phase II Trial of Avelumab in Chemo-resistant Gestational Trophoblastic Neoplasias (GTN)

Trial Profile

A Phase II Trial of Avelumab in Chemo-resistant Gestational Trophoblastic Neoplasias (GTN)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 22 Nov 2022

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At a glance

  • Drugs Avelumab (Primary)
  • Indications Gestational trophoblastic disease; Trophoblastic tumour
  • Focus Therapeutic Use
  • Acronyms TROPHIMMUN
  • Most Recent Events

    • 16 Nov 2022 Protocol amended as cohort B was stopped for futility.
    • 16 Nov 2022 Results of Cohort B (n=7) assessing the safety and efficacy of Avelumab in patients with gestational trophoblastic tumors with resistance to polychemotherapy published in the Gynecologic Oncology
    • 27 Jul 2020 Results of cohort A (n=15) published in the Journal of Clinical Oncology
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