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A Randomized Phase III Study of Pembrolizumab Given Concomitantly With Chemoradiation and as Maintenance Therapy Versus Chemoradiation Alone in Subjects With Locally Advanced Head and Neck Squamous Cell Carcinoma (KEYNOTE-412)

Trial Profile

A Randomized Phase III Study of Pembrolizumab Given Concomitantly With Chemoradiation and as Maintenance Therapy Versus Chemoradiation Alone in Subjects With Locally Advanced Head and Neck Squamous Cell Carcinoma (KEYNOTE-412)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 01 Oct 2024

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At a glance

  • Drugs Pembrolizumab (Primary) ; Cisplatin
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms KEYNOTE-412
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 18 Sep 2024 This trial has been completed in Poland (Global end date: 2024-08-21) according to European Clinical Trials Database record.
  • 15 Sep 2024 This trial has been completed in France (Global end date: 21 Aug 2024).
  • 05 Sep 2024 This trial has been completed in Belgium (Global end date: 21 Aug 2024).

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