Trial Profile

A Phase III, Randomized, Multicenter, Open-Label, Comparative Study to Determine the Efficacy of Durvalumab or Durvalumab and Tremelimumab in Combination With Platinum-Based Chemotherapy for the First-Line Treatment in Patients with Extensive Disease Small-Cell Lung Cancer (SCLC) (CASPIAN)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 19 Apr 2025

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At a glance

Drugs Durvalumab (Primary) ; Tremelimumab (Primary) ; Carboplatin; Cisplatin; Etoposide
Indications Small cell lung cancer
Focus Registrational; Therapeutic Use
Acronyms CASPIAN
Sponsors AstraZeneca; AstraZeneca AB

22 Jan 2025 Planned End Date changed from 31 Dec 2024 to 31 Dec 2025.
15 May 2024 Planned End Date changed from 29 Mar 2024 to 31 Dec 2024.
12 May 2024 This trial has been completed in Czechia, according to European Clinical Trials Database record.

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