Trial Profile

A Phase IIa Trial of sEphB4-HSA in Combination With Anti PD-1 Antibody (Pembrolizumab, MK3475) in Patients With Non-small Cell Lung and Head/Neck Cancer

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 27 Oct 2025

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At a glance

Drugs Pembrolizumab (Primary) ; SEphB4-HSA (Primary)
Indications Carcinoma; Head and neck cancer; Non-small cell lung cancer
Focus Therapeutic Use

Most Recent Events

22 Oct 2025 Protocol has been amended to add new arms (Experimental: Non-Small Cell Lung Cancer Cohort) , it has changed from 1 to 2.
06 Feb 2025 Status changed from active, no longer recruiting to completed.
14 Mar 2024 Planned End Date changed from 10 Mar 2025 to 10 Mar 2026.

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