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Phase Ib/II Study of the Glutaminase Inhibitor CB-839 in Combination With Azacitidine in Patients With Advanced Myelodysplastic Syndrome

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Trial Profile

Phase Ib/II Study of the Glutaminase Inhibitor CB-839 in Combination With Azacitidine in Patients With Advanced Myelodysplastic Syndrome

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 17 May 2024

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At a glance

  • Drugs Azacitidine (Primary) ; Azacitidine (Primary) ; Telaglenastat (Primary)
  • Indications Chronic myelomonocytic leukaemia; Myelodysplastic syndromes; Refractory anaemia
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 22 Apr 2024 Protocol has been amended to modification and change in primary endpoint of the study.
  • 17 Mar 2023 Status changed from active, no longer recruiting to completed.
  • 22 Sep 2022 Planned primary completion date changed from 1 Apr 2022 to 1 Apr 2023.

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