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Phase IB/II Open-label Single Arm Study to Evaluate Safety and Efficacy of Tucatinib in Combination With Palbociclib and Letrozole in Subjects With Hormone Receptor Positive and HER2-positive Metastatic Breast Cancer

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Trial Profile

Phase IB/II Open-label Single Arm Study to Evaluate Safety and Efficacy of Tucatinib in Combination With Palbociclib and Letrozole in Subjects With Hormone Receptor Positive and HER2-positive Metastatic Breast Cancer

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 31 Oct 2023

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At a glance

  • Drugs Letrozole (Primary) ; Palbociclib (Primary) ; Tucatinib (Primary)
  • Indications Advanced breast cancer; HER2 positive breast cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TULiP

    • Most Recent Events

    • 02 Oct 2023 Status changed from active, no longer recruiting to completed.
    • 26 Jun 2023 Results assessing the safety and efficacy of of tucatinib, letrozole and palbociclib in patients with metastatic breast cancer, published in the Clinical Cancer Research.
    • 08 Mar 2022 Planned End Date changed from 31 Mar 2023 to 31 Mar 2024.

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