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A Phase 1 Study to Assess Mass Balance, Pharmacokinetics, and Metabolism of [14C]-Pevonedistat in Patients With Advanced Solid Tumors

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Trial Profile

A Phase 1 Study to Assess Mass Balance, Pharmacokinetics, and Metabolism of [14C]-Pevonedistat in Patients With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 09 May 2022

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At a glance

  • Drugs Pevonedistat (Primary) ; Carboplatin; Docetaxel; Paclitaxel
  • Indications Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Takeda Oncology

    • Most Recent Events

    • 03 May 2022 Results of metabolism and clearance mechanisms of pevonedistat in cancer patients, published in the Drug Metabolism and Disposition
    • 22 Oct 2020 Results published in the Investigational New Drugs
    • 13 Nov 2018 Status changed from active, no longer recruiting to completed.

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