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A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of ISIS 416858 (IONIS-FXIRX, an Antisense Inhibitor of Factor XI), Administered Subcutaneously to Patients With End-Stage Renal Disease on Hemodialysis

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Trial Profile

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of ISIS 416858 (IONIS-FXIRX, an Antisense Inhibitor of Factor XI), Administered Subcutaneously to Patients With End-Stage Renal Disease on Hemodialysis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 Jan 2023

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At a glance

  • Drugs IONIS FXIRx (Primary)
  • Indications Thrombosis; Venous thromboembolism
  • Focus Adverse reactions; Pharmacodynamics; Pharmacokinetics
  • Acronyms EMERALD
  • Sponsors Ionis Pharmaceuticals

    • Most Recent Events

    • 10 Aug 2019 The trial has been completed in Bulgarian Drug Agency, according the European Clinical Trials Database record.
    • 06 Aug 2019 Status changed from active, no longer recruiting to completed.
    • 31 Jul 2019 The trial has been completed in Latvia, according the European Clinical Trials Database record.

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