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A Phase 1b Dose-Escalation Study of Cabozantinib (XL184) Administered Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Trial Profile

A Phase 1b Dose-Escalation Study of Cabozantinib (XL184) Administered Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Dec 2018

At a glance

  • Drugs Atezolizumab (Primary) ; Cabozantinib (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; Bladder cancer; Colorectal cancer; Endometrial cancer; Fallopian tube cancer; Gastric cancer; Head and neck cancer; Liver cancer; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Peritoneal cancer; Prostate cancer; Renal cell carcinoma; Solid tumours; Thyroid cancer; Ureteral neoplasms; Urethral cancer; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms COSMIC-021
  • Sponsors Exelixis
  • Most Recent Events

    • 22 Oct 2018 According to an Exelixis media release, results from the dose escalation phase of the study were presented during a poster session at the European Society for Medical Oncology (ESMO) 2018 Congress.
    • 22 Oct 2018 Results from the dose escalation phase of the study (August 21, 2018 data cut-off), presented in an Exelixis media release.
    • 08 Oct 2018 According to an Exelixis media release, data from this trial will be presented at the European Society for Medical Oncology (ESMO) 2018 Congress.
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