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A Phase Ib, Randomized, Blinded, Placebo-Controlled, Multiple Ascending-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous BFKB8488A in Patients With Type 2 Diabetes Mellitus and Patients With Non-Alcoholic Fatty Liver Disease

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Trial Profile

A Phase Ib, Randomized, Blinded, Placebo-Controlled, Multiple Ascending-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous BFKB8488A in Patients With Type 2 Diabetes Mellitus and Patients With Non-Alcoholic Fatty Liver Disease

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Aug 2022

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At a glance

  • Drugs Fazpilodemab (Primary)
  • Indications Non-alcoholic fatty liver disease; Type 2 diabetes mellitus
  • Focus Adverse reactions
  • Sponsors Genentech

    • Most Recent Events

    • 22 Aug 2022 Results assessing safety, tolerability, pharmacokinetics, immunogenicity, and pharmacodynamics of BFKB8488A in patients with type 2 diabetes mellitus (T2DM) or NAFLD published in the Hepatology
    • 25 Mar 2020 Status changed from active, no longer recruiting to completed.
    • 25 Feb 2020 Planned End Date changed from 13 Dec 2019 to 1 Mar 2020.

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