Phase I Study of the Pan-ERBB Inhibitor Neratinib Given in Combination With Everolimus, Palbociclib or Trametinib in Advanced Cancer Subjects With EGFR Mutation/Amplification, HER2 Mutation/Amplification or HER3/4 Mutation

Trial Profile

Phase I Study of the Pan-ERBB Inhibitor Neratinib Given in Combination With Everolimus, Palbociclib or Trametinib in Advanced Cancer Subjects With EGFR Mutation/Amplification, HER2 Mutation/Amplification or HER3/4 Mutation

Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Jun 2018

At a glance

  • Drugs Neratinib (Primary) ; Everolimus; Palbociclib; Trametinib
  • Indications Solid tumours
  • Focus Adverse reactions
  • Most Recent Events

    • 05 Jun 2018 Trial design presented at the 54th Annual Meeting of the American Society of Clinical Oncology
    • 26 Mar 2018 Planned End Date changed from 1 Oct 2022 to 1 Oct 2023.
    • 31 Oct 2017 Planned End Date changed from 1 Apr 2023 to 1 Oct 2022.
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