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Phase I Study of the Pan-ERBB Inhibitor Neratinib Given in Combination With Everolimus, Palbociclib, or Trametinib in Advanced Cancer Subjects With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

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Trial Profile

Phase I Study of the Pan-ERBB Inhibitor Neratinib Given in Combination With Everolimus, Palbociclib, or Trametinib in Advanced Cancer Subjects With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 09 Jul 2024

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At a glance

  • Drugs Neratinib (Primary) ; Everolimus; Palbociclib; Trametinib
  • Indications Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 14 Jun 2023 Planned End Date changed from 1 Oct 2023 to 1 Oct 2025.
    • 14 Jun 2023 Planned primary completion date changed from 1 Oct 2023 to 1 Oct 2025.
    • 14 Jun 2023 Status changed from recruiting to active, no longer recruiting.

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