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A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared With Investigator Choice in HLA-A*0201 Positive Patients With Previously Untreated Advanced Uveal Melanoma

Trial Profile

A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared With Investigator Choice in HLA-A*0201 Positive Patients With Previously Untreated Advanced Uveal Melanoma

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 25 Apr 2025

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At a glance

  • Drugs Tebentafusp (Primary) ; Dacarbazine; Ipilimumab; Pembrolizumab
  • Indications Uveal melanoma
  • Focus Registrational; Therapeutic Use
  • Acronyms ATOM
  • Sponsors Immunocore

Most Recent Events

  • 22 Apr 2025 Planned End Date changed from 1 Jun 2025 to 1 Jul 2025.
  • 01 Mar 2025 Results evaluating safety and efficacy of tebentafusp (IMCgp100) compared with Investigator's Choice (dacarbazine, ipilimumab or pembrolizumab) published in the Journal of Investigative Dermatology.
  • 10 Jan 2025 According to an Immunocore media release, data from the study is expected in 2026.

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