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A Phase I Trial of B-cell Maturation Antigen (BCMA) Targeted EGFRt/BCMA-41BBz Chimeric Antigen Receptor (CAR) Modified T Cells With or Without Lenalidomide for the Treatment of Multiple Myeloma (MM)

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Trial Profile

A Phase I Trial of B-cell Maturation Antigen (BCMA) Targeted EGFRt/BCMA-41BBz Chimeric Antigen Receptor (CAR) Modified T Cells With or Without Lenalidomide for the Treatment of Multiple Myeloma (MM)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 18 Mar 2026

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At a glance

  • Drugs Orvacabtagene autoleucel (Primary) ; Cyclophosphamide; Fludarabine; Lenalidomide
  • Indications Multiple myeloma
  • Focus Adverse reactions

Most Recent Events

  • 04 Mar 2026 Planned End Date changed from 1 Feb 2026 to 1 Feb 2027.
  • 04 Mar 2026 Planned primary completion date changed from 1 Feb 2026 to 1 Feb 2027.
  • 04 Mar 2025 Planned End Date changed from 1 Feb 2025 to 1 Feb 2026.

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