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A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial Testing Ipatasertib Plus Abiraterone Plus Prednisone/Prednisolone, Relative to Placebo Plus Abiraterone Plus Prednisone/Prednisolone in Adult Male Patients With Asymptomatic or Mildly Symptomatic, Previously Untreated, Metastatic Castrate-Resistant Prostate Cancer

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Trial Profile

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial Testing Ipatasertib Plus Abiraterone Plus Prednisone/Prednisolone, Relative to Placebo Plus Abiraterone Plus Prednisone/Prednisolone in Adult Male Patients With Asymptomatic or Mildly Symptomatic, Previously Untreated, Metastatic Castrate-Resistant Prostate Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 09 Jun 2025

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At a glance

  • Drugs Ipatasertib (Primary) ; Abiraterone; Abiraterone acetate; Prednisolone; Prednisone
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms IPATential150
  • Sponsors Chugai Pharmaceutical; Roche

Most Recent Events

  • 01 Jun 2025 Results assessing final overall survival and molecular data associated with clinical outcome in patients receiving ipatasertib and abiraterone were published in the European Urology.
  • 22 May 2024 Status changed from active, no longer recruiting to completed.
  • 09 May 2024 This trial has been completed in Germany (Global end date: 24 Apr 2024).

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