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Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate Safety, Tolerability, and Efficacy of Ixekizumab in Patients From 6 to Less Than 18 Years of Age With Moderate-to-Severe Plaque Psoriasis

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Trial Profile

Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate Safety, Tolerability, and Efficacy of Ixekizumab in Patients From 6 to Less Than 18 Years of Age With Moderate-to-Severe Plaque Psoriasis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 12 May 2023

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At a glance

  • Drugs Ixekizumab (Primary) ; Etanercept
  • Indications Plaque psoriasis
  • Focus Registrational; Therapeutic Use
  • Acronyms Ixora-peds
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 21 Mar 2023 Results of post-hoc pooled analysis assessing the disease improvement and clearance of palmoplantar PsO in the palms and soles of patients with moderate-to-severe plaque PsO and baseline palmoplantar PsO who were treated with ixekizumab for up to 5 years across 6 clinical trials (NCT01474512, NCT01597245, NCT01646177, NCT03364309, NCT02561806 and NCT03073200), presented at the American Academy of Dermatology annual Meeting 2023.
    • 21 Mar 2023 Results assessing to compare the efficacy of ixekizumab versus secukinumab in pediatric patients with severe plaque psoriasis from IXORA-PEDS and CAIN457A2310 using matching-adjusted indirect comparison, presented at the American Academy of Dermatology annual Meeting 2023.
    • 13 Apr 2022 Results assessing long-term efficacy and safety of Up to 108 Weeks of Ixekizumab published in the JAMA Dermatology

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