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Phase I trial of nivolumab in pediatric patients with malignant solid tumors or Hodgkin lymphoma

Trial Profile

Phase I trial of nivolumab in pediatric patients with malignant solid tumors or Hodgkin lymphoma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Nov 2022

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At a glance

  • Drugs Nivolumab (Primary)
  • Indications Hodgkin's disease; Solid tumours
  • Focus Adverse reactions
  • Acronyms PENGUIN
  • Most Recent Events

    • 31 Oct 2022 Status changed from active, no longer recruiting to completed.
    • 23 Mar 2021 Planned End Date changed from 31 Mar 2021 to 31 Mar 2022.
    • 28 Jan 2021 According to an Ono Pharmaceutical media release, the company has submitted a supplemental application for Opdivo (generic name: nivolumab) Intravenous Infusion in Japan to expand the use for the treatment of pediatric patients with recurrent or refractory classical Hodgkin lymphoma for a partial change in approved items of the manufacturing and marketing approval, based on data from this trial.
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