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A Phase 1, First-in-Human, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety and Immunogenicity of H10N8 Antigen mRNA in Healthy Adult Subjects

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Trial Profile

A Phase 1, First-in-Human, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety and Immunogenicity of H10N8 Antigen mRNA in Healthy Adult Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs MRNA 1440 (Primary)
  • Indications Influenza A virus infections
  • Focus Adverse reactions; First in man; Proof of concept
  • Sponsors Moderna Therapeutics

    • Most Recent Events

    • 10 May 2019 According to a Moderna Therapeutics media release, data from this study and NCT03345043 has been published in journal Vaccine.
    • 10 May 2019 Results published in the Moderna Therapeutics Media Release
    • 14 Aug 2018 Planned End Date changed from 1 Jun 2018 to 1 Oct 2018.

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