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A Phase IIb, 2-Arm, Randomized, Double-blind, Placebo-Controlled, Multicentre Study to Optimize Diamyd Therapy Administered into Lymph Nodes Combined with Oral Vitamin D to Investigate the Impact on the Progression of Type 1 diabetes

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Trial Profile

A Phase IIb, 2-Arm, Randomized, Double-blind, Placebo-Controlled, Multicentre Study to Optimize Diamyd Therapy Administered into Lymph Nodes Combined with Oral Vitamin D to Investigate the Impact on the Progression of Type 1 diabetes

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 31 Jan 2024

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At a glance

  • Drugs GAD65 vaccine (Diamyd) (Primary) ; Vitamin D
  • Indications Type 1 diabetes mellitus
  • Focus Pharmacodynamics; Registrational
  • Acronyms DIAGNODE-2
  • Sponsors Diamyd Medical AB

    • Most Recent Events

    • 24 Jan 2024 Results describing significant protective effect of endogenous insulin production on several hypoglycemic measures, (episodes of below normal blood glucose levels), published in the Diamyd Medical AB Media Release.
    • 06 Jun 2022 Results published in the Media Release
    • 06 Jun 2022 Results assessing the efficacy of intralymphatic GAD-alum on blood glucose recorded by continuous glucose monitoring published in the Journal of Clinical Endocrinology and Metabolism

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