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Phase 1, 3-Part, Open-Label Study to Assess Safety, Tolerability and PK of Single and Multiple Doses of PUR1900 in Healthy Subjects and Crossover Study of Single Doses of PUR1900 and Sporanox in Adult Subjects With Mild to Moderate Asthma

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Trial Profile

Phase 1, 3-Part, Open-Label Study to Assess Safety, Tolerability and PK of Single and Multiple Doses of PUR1900 in Healthy Subjects and Crossover Study of Single Doses of PUR1900 and Sporanox in Adult Subjects With Mild to Moderate Asthma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Aug 2023

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At a glance

  • Drugs Itraconazole (Primary) ; Itraconazole
  • Indications Allergic bronchopulmonary aspergillosis; Asthma
  • Focus Adverse reactions; First in man
  • Sponsors Pulmatrix

    • Most Recent Events

    • 23 Aug 2023 According to a Pulmatrix media release, data assessing drug-drug Interactions with inhaled itraconazole using pharmacokinetic Modelling, based on data from this trial were published in the peer-reviewed American Association of Pharmaceutical Scientists (AAPS) Journal.
    • 23 Aug 2023 Results presented in the Pulmatrix Media Release.
    • 06 Nov 2019 Results assessing safety, tolerability and pharmacokinetics of PUR1900 in healthy volunteers and patients with Asthma published in the British Journal of Clinical Pharmacology

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