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An Open-Label, Multi-Center Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With REGN2810 in Subjects With Newly-Diagnosed Glioblastoma (GBM)

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Trial Profile

An Open-Label, Multi-Center Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With REGN2810 in Subjects With Newly-Diagnosed Glioblastoma (GBM)

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 May 2024

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At a glance

  • Drugs Cemiplimab (Primary) ; INO 5401 (Primary) ; INO 9012 (Primary) ; Temozolomide (Primary)
  • Indications Glioblastoma
  • Focus Adverse reactions
  • Sponsors Inovio Pharmaceuticals
  • Most Recent Events

    • 14 May 2024 Planned End Date changed from 31 Dec 2023 to 31 Dec 2024.
    • 14 May 2024 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2024.
    • 06 Mar 2024 According to Invio Therapeutics media release, through 2023, patients involved in the trial continued to receive drug. In the first half of 2024, INOVIO expects to finalize next steps for further development of INO-5401 in conjunction with Regeneron and investigators.

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