Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Dose Escalation Trial to Determine Safety and Development of Protective Efficacy After Exposure to Only Pre-erythrocytic Stages of Plasmodium Falciparum
Phase of Trial: Phase I
Latest Information Update: 27 Dec 2018
At a glance
- Drugs Malaria vaccine live attenuated-Sanaria (Primary) ; Pyrimethamine (Primary) ; Chloroquine diphosphate
- Indications Malaria
- Focus Adverse reactions; Therapeutic Use
- 15 Dec 2018 Planned End Date changed from 30 Jun 2019 to 31 Dec 2020.
- 15 Dec 2018 Planned primary completion date changed from 31 Dec 2018 to 30 Jun 2020.
- 30 Dec 2017 Planned End Date changed from 15 Jun 2018 to 30 Jun 2019.