Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Dose Escalation Trial to Determine Safety and Development of Protective Efficacy After Exposure to Only Pre-erythrocytic Stages of Plasmodium Falciparum

Trial Profile

Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Dose Escalation Trial to Determine Safety and Development of Protective Efficacy After Exposure to Only Pre-erythrocytic Stages of Plasmodium Falciparum

Recruiting
Phase of Trial: Phase I

Latest Information Update: 09 May 2018

At a glance

  • Drugs Malaria vaccine live attenuated-Sanaria (Primary) ; Pyrimethamine (Primary) ; Chloroquine diphosphate
  • Indications Malaria
  • Focus Adverse reactions; Therapeutic Use
  • Most Recent Events

    • 30 Dec 2017 Planned End Date changed from 15 Jun 2018 to 30 Jun 2019.
    • 30 Dec 2017 Planned primary completion date changed from 30 Dec 2017 to 31 Dec 2018.
    • 20 Jul 2017 Planned number of patients changed from 200 to 230.
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top