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A Phase III Multicenter Open-label Randomized Trial to Evaluate Efficacy and Safety of Folfirinox (FFX) Versus Combination of CPI-613 With Modified Folfirinox (mFFX) in Patients With Metastatic Adenocarcinoma of the Pancreas

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A Phase III Multicenter Open-label Randomized Trial to Evaluate Efficacy and Safety of Folfirinox (FFX) Versus Combination of CPI-613 With Modified Folfirinox (mFFX) in Patients With Metastatic Adenocarcinoma of the Pancreas

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 Feb 2024

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At a glance

  • Drugs Devimistat (Primary) ; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms AVENGER 500
  • Sponsors Cornerstone Pharmaceuticals Inc

    • Most Recent Events

    • 20 Jan 2024 Results assessing relationships between detailed body composition in patients with metastatic PDA on both overall survival (OS) and progression-free survival (PFS), presented at the 2024 Gastrointestinal Cancers Symposium
    • 07 Jun 2022 Results presented at the 58th Annual Meeting of the American Society of Clinical Oncology
    • 01 Jun 2022 According to Cornerstone Pharmaceuticals Inc media release, data from this study presented at the American Society of Clinical Oncology (ASCO) Annual Meeting.

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