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Randomized, Controlled Study to Compare the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment Given Sequentially Following Cisplatin/Gemcitabine Versus Cisplatin/Gemcitabine in Patients With IntraHepatic Cholangiocarcinoma

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Trial Profile

Randomized, Controlled Study to Compare the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment Given Sequentially Following Cisplatin/Gemcitabine Versus Cisplatin/Gemcitabine in Patients With IntraHepatic Cholangiocarcinoma

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 05 Mar 2024

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At a glance

  • Drugs Melphalan (Primary) ; Cisplatin; Gemcitabine
  • Indications Cholangiocarcinoma
  • Focus Registrational; Therapeutic Use
  • Acronyms ALIGN
  • Sponsors Delcath Systems

    • Most Recent Events

    • 04 Feb 2024 This trial has been discontinued in Italy, according to European Clinical Trials Database record.
    • 27 Oct 2022 This trial has been completed in Germany, according to European Clinical Trials Database record.
    • 21 Apr 2021 According to a Delcath Systems media release, the company have paused their work on this study and they will reevaluate the trial design.

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