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A Single Arm, Open-Label, Multi-Centre, Phase I/II Study Evaluating the Safety and Clinical Activity of AUTO2, a CAR T Cell Treatment Targeting BCMA and TACI, in Patients with Relapsed or Refractory Multiple Myeloma.

Trial Profile

A Single Arm, Open-Label, Multi-Centre, Phase I/II Study Evaluating the Safety and Clinical Activity of AUTO2, a CAR T Cell Treatment Targeting BCMA and TACI, in Patients with Relapsed or Refractory Multiple Myeloma.

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs AUTO 2 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Multiple myeloma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Acronyms APRIL
  • Sponsors Autolus

Most Recent Events

  • 06 Nov 2019 Results (data cut-off date July 03, 2019; n=12) released at the 61st Annual Meeting and Exposition of the American Society of Hematology.
  • 06 Nov 2019 According to an Autolus media release, data from the study will be presented at he 61st American Society of Hematology (ASH) Annual Meeting and Exposition 2019.
  • 15 Oct 2019 Status changed from recruiting to discontinued.

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